Escherichia coli Thr-6
L-threonine producing strain derived from E. coli MG1655.
Ancestors
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Plasmid pEC-XK99E-thrAC1034TBC addedBars (|) indicate differences between strains.
Plasmids
-
pEC-XK99E-thrAC1034TBC (thrAC1034TBC)
Modifications
| Origin | Gene | Organism | Modification |
|---|---|---|---|
|
Feedback insensitive
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|
Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-threonine | Titer | 3.7 g/L | 48 h | Flask | [358] | ||
| 2,5-Dimethylpyrazine | Titer | 0.04 g/L | 48 h | Flask | [358] | ||
| 2,5-Dimethylpyrazine | Titer | 0.07 g/L | 48 h | Flask | [358] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.