tyramine

Description

Tyramine is a key precursor in the engineered tyrosol biosynthetic pathway, produced from tyrosine by tyrosine decarboxylase (TDC) and subsequently converted to 4-hydroxyphenylacetaldehyde (4HPAA) by tyramine oxidase (TYO). In feaB-knockout Escherichia coli strains, this intermediate is efficiently and effectively converted to tyrosol, eliminating diversion toward 4-hydroxyphenylacetate formation [355].

Chemical Formula:

C₈H₁₂NO

Molecular Weight:

138.189 Daltons

Monoisotopic Mass:

138.09188901250002 Daltons

SMILES:

C1(C=C(O)C=CC(CC[N+])=1)

InChI:

1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2/p+1

InChIKey:

DZGWFCGJZKJUFP-UHFFFAOYSA-O

Synonyms

tyrosamine
4-(2-aminoethyl)phenol
p-hydroxyphenethylamine
2-(p-hydroxyphenyl)ethylamine

Databases

MetaCyc: TYRAMINE

RefMet: Tyramine

BiGG: tym

MetaboLights: MTBLC327995

HMDB: HMDB00306

ChemSpider: 4416910

ChEBI: 327995 15760

PubChem (CID): 5249538 5610

CAS: 51-67-2

KEGG: C00483

Seed: cpd00374

MetaNetX: MNXM603

PupChem (SID): 3766

CHEMBL: CHEMBL11608

KNApSAcK: C00001435

PDB-CCD: AEF

3DMET: B01260

NIKKAJI: J4.123H