|
|
1749
|
R1183
R1297
R1296
R1182
R1184
|
|
|
|
1750
|
R1296
R1183
R1182
|
|
|
|
1751
|
|
|
|
|
1752
|
|
|
|
|
1753
|
|
|
|
|
1754
|
|
|
|
|
1755
|
|
|
|
|
1756
|
|
|
|
|
1757
|
|
|
|
|
1758
|
|
|
|
|
1759
|
|
|
|
|
1760
|
|
|
|
|
1761
|
R7194
R1010
R1008
R1009
R1011
|
|
|
|
1762
|
R186
|
|
|
|
1763
|
R998
R997
R999
R989
R988
R990
R991
R996
R994
R992
R995
R993
|
|
|
adk
|
1764
|
R652
R145
R731
R1228
R18
R373
R362
R1229
R570
R679
R1227
R438
|
|
|
|
1765
|
R652
R145
R731
R1228
R18
R373
R1229
R570
R679
R1227
R438
|
|
|
murG
|
1766
|
R95
R681
R643
R120
|
|
|
|
1767
|
R1134
R482
|
|
|
|
1768
|
R1133
R482
|
|
|
|
1769
|
R1133
R1853
R482
|
|
|
pyrH
|
1770
|
R435
|
|
|
cmk
|
1771
|
R435
R425
R187
|
|
|
glyA
|
1772
|
R421
|
|
|
|
1773
|
R1131
|
|
|
|
1774
|
R2013
R2012
R2014
|
|
|
|
1775
|
R1723
|
|
|
|
1776
|
R1111
|
|
|
|
1777
|
R1196
R250
R774
R324
R694
R287
R77
R78
R43
R1197
R749
R157
R1
|
|
|
|
1778
|
R612
R432
R686
R700
|
|
|
|
1779
|
R1107
|
|
|
|
1780
|
R59
R1337
R86
R1338
|
|
|
|
1781
|
R59
R1337
R86
R1338
|
|
|
|
1782
|
R59
R1337
R86
R1338
|
|
|
|
1783
|
R1135
|
|
|
|
1784
|
R211
R714
|
|
|
|
1785
|
R1080
|
|
|
|
1786
|
R2445
R727
|
|
|
|
1787
|
R746
|
|
|
|
1788
|
R2515
|
|
|
|
1789
|
R489
R116
|
|
|
|
1790
|
R969
R1174
R959
R1172
R960
R967
R962
R1170
R296
R963
R964
R966
R965
R961
R968
|
|
|
|
1791
|
R1186
R1185
|
|
|
|
1792
|
R36
|
|
|
|
1793
|
R1833
R1866
R1834
|
|
|
|
1794
|
R1604
|
|
|
|
1795
|
R102
|
|
|
|
1796
|
R759
|
|
|
|
1797
|
R776
|
|
|
lpxC
|
1798
|
R958
|
|
|
|
1799
|
R16
|
|
|
|
1800
|
R16
|
|
|
|
1801
|
R16
|
|
|
|
1802
|
R1155
R1153
R345
R1154
|
|
|
|
1803
|
R372
R584
|
|
|
|
1804
|
R1294
R1179
R553
R1101
R1248
R1100
|
|
|
|
1805
|
R1179
R1248
R553
|
|
|
|
1806
|
R1179
R1248
R553
|
|
|
|
1807
|
R1179
R1248
R553
|
|
|
|
1808
|
R177
|
|
|
rocD
|
1809
|
R892
|
|
|
|
1810
|
R1566
|
|
|
|
1811
|
R1566
|
|
|
|
1812
|
R1866
|
|
|
|
1813
|
R1181
|
|
|
|
1814
|
R485
|
|
|
|
1815
|
R236
|
|
|
amiE
|
1816
|
R1204
R1201
R1205
R1202
R1203
|
|
|
|
1817
|
R986
|
|
|
|
1818
|
R2260
|
|
|
|
1819
|
R2260
|
|
|
|
1820
|
R646
|
|
|
|
1821
|
R1037
|
|
|
|
1822
|
R315
R574
|
|
|
|
1823
|
R1067
R315
R574
|
|
|
|
1824
|
R205
|
|
|
|
1825
|
R1151
R1152
|
|
|
|
1826
|
R672
|
|
|
|
1827
|
R492
R140
R550
|
|
|
|
1828
|
R480
|
|
|
|
1829
|
R1018
|
|
|
|
1830
|
R71
R1333
R1248
R1334
|
|
|
|
1831
|
R1247
R1248
R223
|
|
|
pyrG
|
1832
|
R285
R1248
R1234
|
|
|
guaA
|
1833
|
R1247
R1248
R223
|
|
|
|
1834
|
R805
R1248
R53
|
|
|
carB
|
1835
|
R805
R1248
R53
|
|
|
|
1836
|
R1258
|
|
|
|
1837
|
R736
|
|
|
|
1838
|
R736
|
|
|
|
1839
|
R764
R1232
R180
|
|
|
|
1840
|
R658
R690
R977
R1902
R3677
|
|
|
|
1841
|
R1246
|
|
|
|
1842
|
R328
|
|
|
|
1843
|
R635
R378
R758
|
|
|
|
1844
|
R31
|
|
|
|
1845
|
R350
R653
|
|
|
|
1846
|
R309
|
|
|
|
1847
|
R3340
|
|
|
|
1848
|
R216
R384
R583
|
|
|
|
1849
|
R735
R640
|
|
|
|
1850
|
R68
R400
|
|
|
|
1851
|
R210
|
|
|
glmU
|
1852
|
R259
|
|
|
|
1853
|
R430
R1128
R1129
|
|
|
|
1854
|
R430
R1128
R1129
|
|
|
|
1855
|
R444
R365
|
|
|
|
1856
|
R1453
|
|
|
|
1857
|
R1032
R1453
|
|
|
|
1858
|
R184
R509
R454
|
|
|
|
1859
|
R1390
|
|
|
|
1860
|
R392
|
|
|
|
1861
|
R392
|
|
|
|
1862
|
R176
|
|
|
|
1863
|
R227
R224
R586
|
|
|
|
1864
|
R586
R597
|
|
|
|
1865
|
R586
R597
|
|
|
|
1866
|
R586
R597
|
|
|
|
1867
|
R586
R597
|
|
|
|
1868
|
R586
|
|
|
|
1869
|
R586
|
|
|
|
1870
|
R586
|
|
|
|
1871
|
R586
|
|
|
|
1872
|
R586
|
|
|
|
1873
|
R2088
R249
R2089
|
|
|
|
1874
|
R126
|
|
|
|
1875
|
R202
|
|
|
ispG
|
1876
|
R604
|
|
|
|
1877
|
R3715
R300
|
|
|
|
1878
|
R1238
R1236
R1240
R1237
R1239
|
|
|
|
1879
|
R618
|
|
|
|
1880
|
R1404
|
|
|
|
1881
|
R597
|
|
|
|
1882
|
R848
|
|
|
hisD
|
1883
|
R613
R229
R204
|
|
|
|
1884
|
R146
|
|
|
anmK
|
1885
|
R1002
|
|
|
thyX
|
1886
|
R1261
|
|
|
|
1887
|
R1913
|
|
|
|
1888
|
R619
R1206
R60
|
|
|
|
1889
|
R423
|
|
|
|
1890
|
R554
R505
|
|
|
|
1891
|
R1218
|
|
|
|
1892
|
R664
R269
R684
R588
R1434
|
|
|
|
1893
|
R664
R1434
R684
|
|
|
|
1894
|
R664
R1434
R684
|
|
|
|
1895
|
R627
R264
R527
|
|
|
|
1896
|
|
|
|
|
1897
|
|
|
|
|
1898
|
R463
R397
|
|
|
mraY
|
1899
|
R83
R20
R38
|
|
|
|
1900
|
R1399
R182
R12
|
|
|
|
1901
|
R1034
R9
R1006
|
|
|
|
1902
|
R353
|
|
|
|
1903
|
R27
|
|
|
|
1904
|
R27
|
|
|
|
1905
|
R1223
|
|
|
glgC
|
1906
|
R1553
|
|
|
|
1907
|
R1096
|
|
|
|
1908
|
R7
|
|
|
|
1909
|
R1075
|
|
|
|
1910
|
R1263
R549
|
|
|
|
1911
|
R270
|
|
|
|
1912
|
R270
|
|
|
|
1913
|
R1253
R659
|
|
|
|
1914
|
R947
|
|
|
sucC
|
1915
|
R1049
|
|
|
|
1916
|
R1049
|
|
|
|
1917
|
R1049
|
|
|
|
1918
|
R1049
|
|
|
|
1919
|
R1025
|
|
|
|
1920
|
R140
R550
R142
|
|
|
|
1921
|
R1612
|
|
|
|
1922
|
R1014
R1216
R1215
|
|
|
|
1923
|
R511
|
|
|
|
1924
|
R1150
|
|
|
|
1925
|
R506
R599
|
|
|
proA
|
1926
|
R726
|
|
|
|
1927
|
R1438
|
|
|
|
1928
|
R443
|
|
|
|
1929
|
R568
|
|
|
hisG
|
1930
|
R568
|
|
|
|
1931
|
R1019
|
|
|
|
1932
|
R1199
R1198
|
|
|
|
1933
|
R92
|
|
|
|
1934
|
R413
|
|
|
|
1935
|
R81
|
|
|
|
1936
|
R247
R81
|
|
|
|
1937
|
R417
|
|
|
|
1938
|
R647
|
|
|
|
1939
|
R10563
|
|
|
|
1940
|
R10563
|
|
|
|
1941
|
R10563
|
|
|
|
1942
|
R2199
|
|
|
|
1943
|
R2199
|
|
|
|
1944
|
R1145
R1144
|
|
|
|
1945
|
R1145
R1144
|
|
|
|
1946
|
R1145
R1144
|
|
|
|
1947
|
R1145
R1144
|
|
|
|
1948
|
R1145
R1144
|
|
|
|
1949
|
R1145
R1144
|
|
|
|
1950
|
R2640
R2959
|
|
|
|
1951
|
R1664
|
|
|
argD
|
1952
|
R900
R559
|
|
|
|
1953
|
R73
|
|
|
purH
|
1954
|
R207
R119
|
|
|
|
1955
|
R529
|
|
|
glpX
|
1956
|
R241
|
|
|
|
1957
|
R173
|
|
|
|
1958
|
R173
|
|
|
|
1959
|
R195
|
|
|
|
1960
|
R195
|
|
|
|
1961
|
R820
R1637
|
|
|
|
1962
|
R52
|
|
|
|
1963
|
R215
R1226
|
|
|
|
1964
|
R215
R1226
|
|
|
|
1965
|
R215
R1226
|
|
|
|
1966
|
R1216
R1215
|
|
|
|
1967
|
R738
R380
|
|
|
|
1968
|
R281
|
|
|
|
1969
|
R1883
R1882
|
|
|
|
1970
|
R331
|
|
|
|
1971
|
R331
|
|
|
|
1972
|
R331
|
|
|
|
1973
|
R331
|
|
|
|
1974
|
R196
R674
|
|
|
|
1975
|
R590
R185
R637
R498
R128
|
|
|
|
1976
|
R1117
R1118
R1115
R1116
|
|
|
|
1977
|
R973
|
|
|
|
1978
|
R955
|
|
|
|
1979
|
R135
R1220
|
|
|
|
1980
|
R143
|
|
|
|
1981
|
R457
|
|
|
dcd
|
1982
|
R1259
R1260
|
|
|
|
1983
|
R426
R1085
R1084
|
|
|
|
1984
|
R562
|
|
|
|
1985
|
R1157
|
|
|
|
1986
|
R1029
R1028
|
|
|
|
1987
|
R594
|
|
|
|
1988
|
R524
|
|
|
|
1989
|
R178
|
|
|
|
1990
|
R178
|
|
|
pyrE
|
1991
|
R680
|
|
|
|
1992
|
R1210
R1211
|
|
|
leuS
|
1993
|
R777
|
|
|
|
1994
|
R571
R1190
R237
R1189
|
|
|
|
1995
|
R1071
R1069
R1070
|
|
|
|
1996
|
R1071
R1069
R1070
|
|
|
|
1997
|
R291
|
|
|
|
1998
|
R291
|
|
|
|
1999
|
R291
|
|
|
pdxA
|
2000
|
R1295
R751
|
|
|
leuD
|
2001
|
R179
R645
R220
|
|
|
|
2002
|
R179
R645
R220
|
|
|
|
2003
|
R766
|
|
|
|
2004
|
R978
R769
|
|
|
|
2005
|
R978
R769
|
|
|
|
2006
|
R1136
R14
|
|
|
|
2007
|
R1589
|
|
|
|
2008
|
R25
|
|
|
|
2009
|
R25
|
|
|
|
2010
|
R25
|
|
|
|
2011
|
R1590
R1592
R1591
R26
|
|
|
|
2012
|
R1112
R1113
|
|
|
|
2013
|
R1327
|
|
|
|
2014
|
R1249
R1250
|
|
|
|
2015
|
R1219
R614
|
|
|
|
2016
|
R575
|
|
|
|
2017
|
R977
R658
R690
|
|
|
|
2018
|
R977
R658
R690
|
|
|
sdhA
|
2019
|
R2057
|
|
|
|
2020
|
R1224
R669
R131
|
|
|
|
2021
|
R650
|
|
|
|
2022
|
R1015
|
|
|
|
2023
|
R1015
|
|
|
|
2024
|
R1015
|
|
|
|
2025
|
R657
|
|
|
|
2026
|
R657
|
|
|
|
2027
|
R657
|
|
|
truA
|
2028
|
R657
|
|
|
|
2029
|
R657
|
|
|
truB
|
2030
|
R657
|
|
|
|
2031
|
R729
|
|
|
|
2032
|
R242
R337
|
|
|
|
2033
|
R624
R418
|
|
|
|
2034
|
R1166
|
|
|
|
2035
|
R1160
R1163
R1158
R1159
R1162
R1161
|
|
|
|
2036
|
R122
|
|
|
|
2037
|
R721
R154
|
|
|
|
2038
|
R1336
R142
|
|
|
|
2039
|
R325
R1616
R1615
R558
R1464
|
|
|
|
2040
|
R325
R1616
R1615
R558
R1464
|
|
|
|
2041
|
R592
|
|
|
|
2042
|
R367
|
|
|
|
2043
|
R868
|
|
|
|
2044
|
R2787
R868
|
|
|
|
2045
|
R2787
R868
|
|
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2046
|
R868
|
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2047
|
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|
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2048
|
R56
|
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2049
|
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|
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2050
|
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R558
|
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2051
|
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|
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2052
|
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|
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2053
|
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|
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2054
|
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R1352
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|
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2055
|
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|
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2056
|
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|
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|
2057
|
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|
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2058
|
R79
R460
|
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2059
|
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R460
|
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2060
|
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R149
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R404
R544
R199
|
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2061
|
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|
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2062
|
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|
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2063
|
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|
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2064
|
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|
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2065
|
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|
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2066
|
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R188
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|
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2067
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|
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2068
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|
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2069
|
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R368
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|
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2070
|
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|
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2071
|
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|
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2072
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|
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2073
|
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|
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|
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2075
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|
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2076
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|
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2077
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|
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2078
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|
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2079
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R825
R1888
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|
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2080
|
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R1305
|
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2081
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R1305
|
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2082
|
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R1305
|
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2083
|
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R1305
|
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2084
|
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|
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2085
|
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R1305
|
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2086
|
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|
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2087
|
R957
|
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2088
|
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|
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2089
|
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|
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2090
|
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|
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2091
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|
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2092
|
R37
|
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2093
|
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|
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2094
|
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R829
|
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2095
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|
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2096
|
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R734
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2097
|
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R734
R363
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2098
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R734
R363
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2099
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|
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2100
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|
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2101
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|
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2102
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R24
|
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2103
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2104
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2105
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|
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2106
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2107
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|
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2108
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2110
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|
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2111
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2112
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2113
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2114
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R1079
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2115
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R1241
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2116
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R1255
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2117
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2118
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|
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2119
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|
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2120
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2121
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2122
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2123
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|
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purN
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2124
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|
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2125
|
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|
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2126
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R1142
|
|
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trpA
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2127
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R503
R747
R508
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2128
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R503
R747
R508
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2129
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R593
|
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2130
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2131
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R175
R609
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R246
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2133
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R69
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R404
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2135
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2136
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2137
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R641
R548
R91
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2138
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R313
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2139
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R565
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2140
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|
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|
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2142
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murD
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2143
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R302
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2144
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|
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2145
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R150
|
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2146
|
R10
|
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2147
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R698
|
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2148
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R561
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|
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2150
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2151
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R407
|
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2152
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|
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|
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2154
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|
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murE
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2155
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R762
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2156
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R656
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2157
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R283
|
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2158
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|
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2160
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2161
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R34
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2162
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R1559
|
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2163
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|
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2165
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2166
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R279
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|
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2168
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R61
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R2711
R112
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2170
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R1056
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2171
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2172
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R547
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2173
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R547
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2174
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R390
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2175
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2176
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2177
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R115
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|
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2179
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2180
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2181
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2182
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R440
|
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2183
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2184
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2185
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R621
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2186
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R621
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2187
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2188
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2189
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2190
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R192
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2191
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R192
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2192
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R192
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2193
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R192
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2194
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2195
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R192
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2196
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|
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2198
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eno
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2199
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R273
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2200
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2201
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R396
R555
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2202
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R1104
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2203
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R339
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2205
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uvrC
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2206
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2207
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R5464
|
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R1139
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2209
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R1776
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R261
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hemE
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R44
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ilvH
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2212
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R277
R545
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R545
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metX
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2214
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2215
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R538
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R342
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2217
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2219
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2220
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R58
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R327
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2222
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R1317
|
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2223
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|
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|
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|
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2225
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R11
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R11
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2227
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R11
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R221
|
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2229
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|
|
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2230
|
R573
|
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2231
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R32
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2232
|
R502
|
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2233
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R1988
|
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2234
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R1988
|
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2235
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R382
R639
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2236
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R436
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R427
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2238
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R605
R631
|
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2239
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R2315
|
|
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2240
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R244
|
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2241
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R379
|
|
|
mmuM
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2242
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R1357
|
|
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2243
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R1003
|
|
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2244
|
R644
|
|
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2245
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R231
|
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2246
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R1001
|
|
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2247
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R153
|
|
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2248
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R10248
|
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2250
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2251
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R232
|
|
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2252
|
R1561
|
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2253
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|
|
|
mtnA
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2254
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R1214
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|
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2255
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R501
|
|
|
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2256
|
R1060
|
|
|
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2257
|
R1060
|
|
|
fumC
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2258
|
R55
|
|
|
|
2259
|
R55
|
|
|
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2260
|
R768
|
|
|
murC
|
2261
|
R671
|
|
|
|
2262
|
R641
|
|
|
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2263
|
R535
|
|
|
folE
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2264
|
R522
|
|
|
|
2265
|
R1032
|
|
|
|
2266
|
R687
|
|
|
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2267
|
R1863
|
|
|
|
2268
|
R171
|
|
|
|
2269
|
R1132
|
|
|
ddl
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2270
|
R528
|
|
|
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2271
|
R408
|
|
|
|
2272
|
R607
|
|
|
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2273
|
R129
|
|
|
|
2274
|
R275
|
|
|
|
2275
|
R1861
|
|
|
pgk
|
2276
|
R655
|
|
|
|
2277
|
R975
|
|
|
murB
|
2278
|
R228
|
|
|
|
2279
|
R1222
|
|
|
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2280
|
R225
|
|
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hisH
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2281
|
R225
|
|
|
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2282
|
R295
|
|
|
|
2283
|
R1254
|
|
|
|
2284
|
R464
|
|
|
|
2285
|
R1193
|
|
|
|
2286
|
R1193
|
|
|
pyrB
|
2287
|
R258
|
|
|
|
2288
|
R1087
|
|
|
|
2289
|
R359
|
|
|
|
2290
|
R359
|
|
|
|
2291
|
R359
|
|
|
tig
|
2292
|
R359
|
|
|
|
2293
|
R359
|
|
|
|
2294
|
R1304
|
|
|
|
2295
|
R518
|
|
|
|
2296
|
R1061
|
|
|
nadE
|
2297
|
R1106
|
|
|
|
2298
|
R322
|
|
|
|
2299
|
R322
|
|
|
|
2300
|
R1245
|
|
|
|
2301
|
R1245
|
|
|
ureC
|
2302
|
R1245
|
|