an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

4-amino-2-methyl-5-pyrimidinemethanol

N⁵-carboxyaminoimidazole ribonucleotide

1,4-dihydroxy-2-naphthoate

S-ribosyl-L-homocysteine

autoinducer 2

(2R,3S)-3-methylmalate

citraconate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

ammonia

hydroxylamine

1-deoxy-L-glycero-tetrulose 4-phosphate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4Z)-2-oxohept-4-enedioate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

pyruvic oxime

1-piperideine 6-carboxylate

(L-threonylcarbamoyl)adenylate

prephytoene diphosphate

γ-L-glutamyl 5-phosphate

coenzyme F₃₉₀-A

4-amino-4-deoxychorismate

hydrogenobyrinate

hexulose 6-phosphate

DNA without lesion

creatinine

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

(S)-2-amino-6-oxohexanoate

urea

2-methyl-trans-aconitate

N²-succinyl-L-glutamate 5-semialdehyde

N²-succinylglutamate

4-acetamidobutanal

4-acetamidobutanoate

5-hydroxytryptophol

5-hydroxyindole acetaldehyde

3-methoxy-4-hydroxyphenylglycolaldehyde

indole-3-glycol

indole-3-glycol aldehyde

isobutanol

3-methylbutanol

3-methylbutanal

2-methylbutanol

2-methylbutanal

2-phenylethanol

(2S)-lactyl-2-diphospho-5'-guanosine

2-phosphoglycolate

glycolate

4-prenylphlorisobutyrophenone

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

(S)-dihydroorotate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

N¹-(5-phospho-β-D-ribosyl)glycinamide

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

D-erythro-imidazole-glycerol-phosphate

nicotinate adenine dinucleotide

arsenite

carbonic acid

imidazole acetol-phosphate

L-histidinol phosphate

N-(5-phosphoribosyl)-anthranilate

anthranilate

β-nicotinate D-ribonucleotide

quinolinate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

pseudouridine 5'-phosphate

prenyl diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

histidinal

histidinol

isopentenyl diphosphate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

L-canavanine

hydrogenobyrinate a,c-diamide

(R)-mevalonate

3-dehydroshikimate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

5-phospho-β-D-ribosylamine

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

3-methyl-2-oxobutanoate

5-aminolevulinate

hydrogen peroxide

5-enolpyruvoyl-shikimate 3-phosphate

shikimate

shikimate 3-phosphate

(R)-5-phosphomevalonate

(R)-mevalonate diphosphate

CDP-glycerol

N-acetylglutamyl-phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

porphobilinogen

preuroporphyrinogen

orotidine 5'-phosphate

citrate

3-phosphooxypyruvate

carbamoyl phosphate

(S)-4-amino-5-oxopentanoate

carbon monoxide

glycerone phosphate

oxaloacetate

α-ribazole

α-ribazole 5'-phosphate

phosphoenolpyruvate

4'-phosphopantetheine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

prephenate

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

H₂

N-acetyl-L-glutamate 5-semialdehyde

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

(2S)-2-isopropylmalate

2-isopropylmaleate

H₂O

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

5-amino-6-(D-ribitylamino)uracil

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

CO₂

thiamine phosphate

thiamine diphosphate

(2E,6E)-farnesyl diphosphate

pristanate

DNA with lesion

adenosylcobalamin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cobyrinate

cob(II)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-precorrin-3

cobalt-factor III

cobalt-precorrin-2

cobalt-sirohydrochlorin

hydrogen cyanide

N₂

uroporphyrinogen-I

uroporphyrinogen-III

oxygen

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

superoxide

dimethyl sulfide

methionol

3-(methylsulfanyl)propanal

thiocyanate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

sulfoacetaldehyde

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

trimethyl sulfonium

sulfite

thiosulfate

nitrite

nitrate

hydrogensulfite

hydrogencarbonate

molybdate

phosphate

triphosphate

diphosphate

Co²⁺

Cu²⁺

Zn²⁺

Mn²⁺

H⁺

Na⁺

ammonium

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

allantoate

(S)-(+)-allantoin

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

methane

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(E)-glutaconyl-CoA

2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

glutaryl-CoA

3'-dephospho-CoA

linoleoyl-CoA

α-linolenoyl-CoA

isobutanoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

succinyl-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

decanoyl-CoA

octanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

menaquinol-8

menaquinol-7

menaquinol-9

menaquinol-6

menaquinol-10

menaquinol-11

menaquinol-12

menaquinol-13

demethylmenaquinol-8

demethylmenaquinol-7

demethylmenaquinol-9

demethylmenaquinol-6

demethylmenaquinol-10

demethylmenaquinol-11

demethylmenaquinol-12

demethylmenaquinol-13

molybdopterin

coenzyme A

methyl-CoM

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

nicotinate

riboflavin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

(S)-1-pyrroline-5-carboxylate

precorrin-3A

precorrin-7

precorrin-8x

precorrin-1

precorrin-5

precorrin-6B

precorrin-6A

precorrin-2

precorrin-3B

precorrin-4

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

molybdopterin adenine dinucleotide

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

adenine

2'-deoxyadenosine

2'-deoxyguanosine

adenosine

hypoxanthine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

XMP

IMP

GMP

AMP

XTP

ITP

GTP

ATP

dCMP

UDP

dUDP

dUTP

dTDP

dTTP

dCDP

dCTP

CDP

UTP

dUMP

dTMP

orotate

uracil

CTP

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-α-D-galactose

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-α-D-glucose

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

cytidine

uridine

UMP

CMP

salicylaldehyde

4-tyrosol

3-methoxy-4-hydroxyphenylglycol

benzaldehyde

(4-hydroxyphenyl)acetaldehyde

phenylacetaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

3,4-dihydroxyphenylglycol

3,4-dihydroxyphenylglycolaldehyde

salicylate

4-aminobenzoate

benzoate

L-α-amino-ε-keto-pimelate

L-serine

creatine

L-leucine

L-proline

L-glutamine

glycine

L-alanine

L-glutamate

L-histidine

L-arginine

L-lysine

L-aspartate

L-cysteine

L-threonine

L-asparagine

L-tyrosine

L-tryptophan

L-phenylalanine

L-saccharopine

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

3-phospho-L-serine

L-citrulline

L-valine

L-isoleucine

L-glutamate-5-semialdehyde

L-canaline

L-homocysteine

L-ornithine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-methionine

L,L-diaminopimelate

chorismate

succinate

fumarate

(S)-malate

cis-2-methylaconitate

(2S,3S)-2-methylcitrate

(R)-2-hydroxybutanoate

(S)-lactate

(R)-lactate

pyruvate

acetate

formate

propanoate

decanoate

octanoate

(15Z)-tetracosenoate

oleate

apo-4'-lycopenoate

linoleate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

α-linolenate

phytenate

palmitate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

2-oxoglutarate

methylglyoxal

diacetyl

6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone

3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone

butan-1-al

1-octanal

1-propanal

isobutanal

acetaldehyde

phytenal

D-glyceraldehyde

α-D-ribofuranose

butan-1-ol

ethanol

propan-1-ol

phytol

(3R)-linalool

(3S)-linalool

myo-inositol

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

di-trans,octa-cis-undecaprenyl phosphate

geranyl diphosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

2-cis,6-trans,10-trans-geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

apo-4'-lycopenal

15-cis-phytoene

all-trans-phytoene

phlorisovalerophenone

deoxyhumulone

4-prenylphlorisovalerophenone

deoxycohumulone

sucrose

β-D-fructofuranose

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

sucrose 6^F-phosphate

α,α-trehalose 6-phosphate

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

α-D-ribose-1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

5'-deoxyadenosine

8-oxo-dGTP

8-oxo-dGMP

cyclic-AMP

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

β-nicotinamide D-ribonucleotide

2-iminosuccinate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

D-alanyl-D-alanine