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H+ + (indol-3-yl)pyruvate → (indol-3-yl)acetaldehyde + CO2 (R2491)
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2-oxoglutarate + L-tryptophan ↔ L-glutamate + (indol-3-yl)pyruvate (R1672)
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H2O + NAD+ + (indol-3-yl)acetaldehyde → H+ + NADH + (indol-3-yl)acetate (R959)
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H2O + L-tryptophan → pyruvate + ammonium + indole (R2069)
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NAD(P)+ + indole-3-ethanol ← NAD(P)H + (indol-3-yl)acetaldehyde (R4930)
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(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate ↔ D-glyceraldehyde 3-phosphate + indole (R503)
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L-serine + indole → H2O + L-tryptophan (R747)
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1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → H2O + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 (R600)
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N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate (R562)
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N-(5-phosphoribosyl)-anthranilate + diphosphate ↔ anthranilate + 5-phospho-α-D-ribose 1-diphosphate (R423)
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L-glutamine + chorismate ↔ anthranilate + pyruvate + H+ + L-glutamate (R10)
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Overexpression
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Feedback insensitive
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D-erythrose 4-phosphate + phosphoenolpyruvate + H2O ↔ 3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (R576)
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NAD+ + 3-phospho-D-glycerate ↔ 3-phosphooxypyruvate + NADH + H+ (R51)
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L-tryptophan + oxygen → H2O + (indol-3-yl)acetamide + CO2 (R818)
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H2O + (indol-3-yl)acetamide → ammonium + (indol-3-yl)acetate (R1203)
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ethanol + NAD+ ↔ acetaldehyde + NADH + H+ (R157)
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coenzyme A + acetaldehyde + NAD+ ↔ NADH + H+ + acetyl-CoA (R156)
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NADP+ + D-threo-isocitrate → NADPH + 2-oxoglutarate + CO2 (R384)
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H+ + L-tryptophan → tryptamine + CO2 (R2731)
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H2O + oxygen + tryptamine → hydrogen peroxide + ammonium + (indol-3-yl)acetaldehyde (R1898)
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α-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate (R140)