β-D-fructofuranose 6-phosphate + ATP → β-D-fructose 1,6-bisphosphate + H⁺ + ADP (R252)
- Silencing
  - Genome
D-gluconate 6-phosphate → H₂O + 2-dehydro-3-deoxy-D-gluconate 6-phosphate (R1789)
- Silencing
  - Genome
2-dehydro-3-deoxy-D-gluconate 6-phosphate → pyruvate + D-glyceraldehyde 3-phosphate (R1404)
- Silencing
  - Genome
H₂O + GTP → H⁺ + 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate (R608)
- Overexpression
  - Plasmid
D-ribulose 5-phosphate → 1-deoxy-L-glycero-tetrulose 4-phosphate + formate + H⁺ (R65)
- Overexpression
  - Plasmid
  - Genome
- Feedback insensitive
  - Genome
5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP⁺ ↔ 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H⁺ (R587)
- Overexpression
  - Plasmid
H₂O + 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H⁺ → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium (R836)
- Overexpression
  - Plasmid
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-(D-ribitylamino)uracil → H₂O + 6,7-dimethyl-8-(1-D-ribityl)lumazine + H⁺ + phosphate (R167)
- Overexpression
  - Plasmid
6,7-dimethyl-8-(1-D-ribityl)lumazine + H⁺ → riboflavin + 5-amino-6-(D-ribitylamino)uracil (R226)
- Overexpression
  - Plasmid
coenzyme A + acetate + ATP ↔ acetyl-CoA + diphosphate + AMP (R1142)
- Overexpression
  - Genome
    - Escherichia coli RF05S-M40
    - Escherichia coli RF05S
riboflavin + ATP → FMN + H⁺ + ADP (R631)
- Attenuation
  - Genome
- Silencing
  - Genome
FMN + H⁺ + ATP → FAD + diphosphate (R605)
- Attenuation
  - Genome
- Silencing
  - Genome
α-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate (R140)
- Silencing
  - Genome
β-D-glucose 6-phosphate + NADP⁺ → 6-phospho D-glucono-1,5-lactone + NADPH + H⁺ (R392)
- Feedback insensitive
  - Plasmid
    - Escherichia coli RF01S/p15Trc-zg
    - Escherichia coli RF01S/p15Trc-zgp
- Overexpression
  - Plasmid
D-gluconate 6-phosphate + NADP⁺ → D-ribulose 5-phosphate + NADPH + CO₂ (R202)
- Feedback insensitive
  - Plasmid
    - Escherichia coli RF01S/p15Trc-zg
    - Escherichia coli RF01S/p15Trc-zgp
- Overexpression
  - Genome
H₂O + 6-phospho D-glucono-1,5-lactone → D-gluconate 6-phosphate + H⁺ (R464)
- Overexpression
  - Plasmid
    - Escherichia coli RF01S/p15Trc-zgp
    - Escherichia coli BL-8
  - Genome
aldehydo-D-ribose 5-phosphate + ATP ↔ 5-phospho-α-D-ribose 1-diphosphate + H⁺ + AMP (R115)
- Overexpression
  - Genome
5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ↔ 5-phospho-α-D-ribose 1-diphosphate + H₂O + L-glutamine (R11)
- Overexpression
  - Genome
ATP + dTDP → ADP + dTTP (R731)
- Overexpression
  - Genome
dGDP + ATP → dGTP + ADP (R570)
- Overexpression
  - Genome
ATP + UDP → ADP + UTP (R373)
- Overexpression
  - Genome
dADP + ATP → ADP + dATP (R438)
- Overexpression
  - Genome
ATP + CDP ↔ ADP + CTP (R652)
- Overexpression
  - Genome
ATP + dCDP → ADP + dCTP (R145)
- Overexpression
  - Genome
GDP + ATP → GTP + ADP (R18)
- Overexpression
  - Genome
ATP + dUDP → ADP + dUTP (R679)
- Overexpression
  - Genome
aldehydo-D-ribose 5-phosphate ↔ D-ribulose 5-phosphate (R143)
- Overexpression
  - Genome
H₂O + NAD⁺ + 1-deoxy-D-xylulose 5-phosphate ← D-ribulose 5-phosphate + NADH + H⁺ (R4744)
- Silencing
  - Genome
    - Escherichia coli R19
    - Escherichia coli R17
aldehydo-D-arabinose 5-phosphate ↔ D-ribulose 5-phosphate (R986)
- Silencing
  - Genome
    - Escherichia coli R15
    - Escherichia coli R17